Concepedia

Cytosolic DNA initiates a vicious circle of aging-related endothelial inflammation and mitochondrial dysfunction via STING: the inhibitory effect of Cilostazol

Zhihua Zheng, Jiaojiao Wang, Jiu-guo Lin, Weile Ye, Jiami Zou, Li-yin Liang, Ping-Lian Yang, Wan-lu Qiu, Yuanyuan Li, Si-jia Yang,

Acta Pharmacologica Sinica · 2024 · 15 citations · 50 references

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Concepts

References

50

A Stable Nonfluorescent Derivative of Resorufin for the Fluorometric Determination of Trace Hydrogen Peroxide: Applications in Detecting the Activity of Phagocyte NADPH Oxidase and Other Oxidases

Mingjie Zhou, Zhenjun Diwu, Nataliya Panchuk-Voloshina et al. · Analytical Biochemistry · 1997 · 1.4K citations

, , +17

Targeting STING with covalent small-molecule inhibitors

Simone M. Haag, Muhammet F. Gülen, Luc Reymond et al. · Nature · 2018 · 1.1K citations · Full text

, , +12

Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

Xu Zhang, Heping Shi, Jiaxi Wu et al. · Molecular Cell · 2013 · 1.1K citations · Full text

, , +10

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

Ali Jazayeri, Jacob Falck, Claudia Lukas et al. · Nature Cell Biology · 2005 · 1K citations

, , +14

cGAS–STING drives ageing-related inflammation and neurodegeneration

Muhammet F. Gülen, Natasha Samson, Alexander Keller et al. · Nature · 2023 · 925 citations · Full text

, , +17