Indole-3-carbinol ameliorates ovarian damage in female old mice through Nrf2/HO-1 pathway activation

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development · 1999 · 3.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

Toru Nakamura, Gregg B. Morin, Karen Chapman et al. · Science · 1997 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Oocyte-Specific Deletion of <i>Pten</i> Causes Premature Activation of the Primordial Follicle Pool

Pradeep Reddy, Lian Liu, Deepak Adhikari et al. · Science · 2008 · 863 citations

Medicine, Genetics, Molecular Genetics +17

Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway

Ruozhi Dang, Mingyang Wang, Xinhui Li et al. · Journal of Neuroinflammation · 2022 · 490 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Kaempferol Ameliorates Oxygen-Glucose Deprivation/Reoxygenation-Induced Neuronal Ferroptosis by Activating Nrf2/SLC7A11/GPX4 Axis

Yuan Yuan, Yanyu Zhai, Jingjiong Chen et al. · Biomolecules · 2021 · 459 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17