Unlocking the anticancer activity of gambogic acid: a shift towards ferroptosis via a GSH/Trx dual antioxidant system

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

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Life Sciences, Biochemistry, Cell Biology +10

Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

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Medicine, Cancer Biology, Oncology +14

Auranofin mitigates systemic iron overload and induces ferroptosis via distinct mechanisms

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Medicine, Immunology, Pharmacology +17

3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis

Nobuaki Takahashi, Patricia Cho, Laura M. Selfors et al. · Molecular Cell · 2020 · 200 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis

Ruijia Wen, Xin Dong, Haowen Zhuang et al. · Phytomedicine · 2023 · 193 citations

Medicine, Cancer Biology, Oncology +6