Arginine methylation of ALKBH5 by PRMT6 promotes breast tumorigenesis via LDHA-mediated glycolysis

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m ⁶ A-demethylation of NANOG mRNA

Chuanzhao Zhang, Debangshu Samanta, Haiquan Lu et al. · Proceedings of the National Academy of Sciences · 2016 · 1K citations · Full text

Medicine, Cancer Biology, Oncology +17

HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g

Xiaoli Cai, Xiao Wang, Can Cao et al. · Cancer Letters · 2017 · 494 citations

Medicine, Genetics, Molecular Biology +16

Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive

Ernesto Guccione, C. Bassi, Fabio Casadio et al. · Nature · 2007 · 489 citations

Life Sciences, Genetics, Molecular Biology +12

ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1

Jun Zhang, Shuai Guo, Haiyan Piao et al. · Journal of Physiology and Biochemistry · 2019 · 322 citations · Full text

Medicine, Cancer Biology, Oncology +17

Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers

Masanori Yoshimatsu, Gouji Toyokawa, Shinya Hayami et al. · International Journal of Cancer · 2010 · 317 citations · Full text

Life Sciences, Molecular Biology, Oncology +14