Concepedia

β-Nicotinamide mononucleotide supplementation prolongs the lifespan of prematurely aged mice and protects colon function in ageing mice

Yanrou Gu, Lidan Gao, Jiamin He, Man Luo, Mei Hu, Yuxian Lin, Jianxin Li, Tongyao Hou, Jianmin Si, Yingcong Yu

Food & Function · 2024 · 13 citations · 42 references

DOIFull text

Open access

Concepts

Abstract

and notable differences in metabolic pathways related to choline metabolism in cancer. In summary, NMN supplementation can delay frailty in old age, aid healthy ageing, and delay gut ageing.

References

42

Gut microbiota composition correlates with diet and health in the elderly

Marcus J. Claesson, Ian B. Jeffery, Susana Conde et al. · Nature · 2012 · 3.3K citations

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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Carles Cantó, Zachary Gerhart‐Hines, Jérôme N. Feige et al. · Nature · 2009 · 3.2K citations · Full text

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Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians

Elena Biagi, Lotta Nylund, Marco Candela et al. · PLoS ONE · 2010 · 1.5K citations · Full text

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Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy

Lukas F. Mager, Regula Burkhard, Nicola Pett et al. · Science · 2020 · 1.3K citations

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Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

Kathryn F. Mills, Shohei Yoshida, Liana R. Stein et al. · Cell Metabolism · 2016 · 896 citations · Full text

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