Role of succinylation modification in central nervous system diseases

Alzheimer's disease

The Lancet · 2021 · 4.9K citations · Full text

Life Sciences, Genetics, Neurology +17

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Lenny Dang, David W. White, Bryson D. Bennett et al. · Nature · 2009 · 4.1K citations · Full text

Medicine, Genetics, Molecular Genetics +10

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Wei Xu, Hui Yang, Ying Liu et al. · Cancer Cell · 2011 · 2.8K citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

Edward T. Chouchani, Victoria R. Pell, Edoardo Gaude et al. · Nature · 2014 · 2.8K citations

Life Sciences, Biochemistry, Physiology +16

CBTRUS Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014

Quinn T. Ostrom, Haley Gittleman, Peter Liao et al. · Neuro-Oncology · 2017 · 1.8K citations · Full text

Medicine, Neurosurgery, Oncology +9