Single-cell characterization of infiltrating T cells identifies novel targets for gallbladder cancer immunotherapy

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu, Li-Gen Wang, Yanyan Han et al. · OMICS A Journal of Integrative Biology · 2012 · 38.3K citations

Life Sciences, Bioinformatics, Biology +13

Global cancer statistics, 2012

Lindsey A. Torre, Freddie Bray, Rebecca L. Siegel et al. · CA A Cancer Journal for Clinicians · 2015 · 27.4K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.7K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

Reversed graph embedding resolves complex single-cell trajectories

Xiaojie Qiu, Qi Mao, Ying Tang et al. · Nature Methods · 2017 · 5.4K citations · Full text

Life Sciences, Biology, Cell Biology +6

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

Christopher S. McGinnis, Lyndsay M. Murrow, Zev J. Gartner · Cell Systems · 2019 · 4.6K citations · Full text

Life Sciences, Bioinformatics, Biology +17