RETRACTED: Superior rat wound-healing activity of green synthesized silver nanoparticles from acetonitrile extract of Juglans regia L: Pellicle and leaves

Abstract

L. pellicle extract (P) has shown significant effectiveness in both models, as well as their bio-reduced partner AgNP/P. The skin's tensile strength following AgNP/P therapy (871 g, p value < 0.05) is comparable to that after Solcoseryl® (928 g), both of which are significantly better than AgNP (592 g) in the incision wound model. Epithelialization time (16.0 and 16.5 days) did not substantially differ from Solcoseryl® (15.3 days) (P value < 0.05). There was an elevated collagen content. Low levels of IL1β (189.0 pg/g) and high levels of TNF-α (1007.1 pg/g) in the case of AgNP/P suggest various cellular kinds of maturation and various wound healing structures that are evident in histopathology investigations. The bioreduced AgNP/P could find use as a pharmaceutical agent for wound healing dressings.