Concepedia

STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response

Lintao Wang, Suya Zhang, Hongxia Liu, Li Gao, Lu He, Yue Chen, Jun-sheng Zhang, Miaomiao Yang, Chaoyong He

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2023 · 14 citations · 27 references

DOI

Concepts

References

27

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

, , +14

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

Siqi Liu, Xin Cai, Jiaxi Wu et al. · Science · 2015 · 1.9K citations

, , +17

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser, Marion Goldeck, Taner Cavlar et al. · Nature · 2013 · 1.6K citations · Full text

, , +12

STING is a direct innate immune sensor of cyclic di-GMP

Dara Burdette, Kathryn M. Monroe, Katia Troha et al. · Nature · 2011 · 1.5K citations

, , +12