Nature · 2011 · 1.5K citations · 23 references
Life SciencesImmunologyMolecular BiologyCell SignalingInnate ImmunitySignal TransductionCyclic Nucleotide SignalingInnate Immune ActivationInnate Immune ReceptorsInnate Immune RecognitionInnate Immune ResponseInnate Immune Signaling PathwaysImmune Recognition ReceptorsInnate Cytokine ResponsesInnate Immune Cytokines
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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
Akinori Takaoka, Zhichao Wang, Myoung Kwon Choi et al. · Nature · 2007 · 1.7K citations
IFI16 is an innate immune sensor for intracellular DNA
Leonie Unterholzner, Sinéad E. Keating, Marcin Baran et al. · Nature Immunology · 2010 · 1.6K citations · Full text