SARS-CoV-2 activates the TLR4/MyD88 pathway in human macrophages: A possible correlation with strong pro-inflammatory responses in severe COVID-19 - Concepedia

Concepedia

Publication | Open Access

SARS-CoV-2 activates the TLR4/MyD88 pathway in human macrophages: A possible correlation with strong pro-inflammatory responses in severe COVID-19

DOI Full Paper Access

37

Citations

71

References

2023

Year

Sabina Sahanic, Richard Hilbe, Christina Dünser, Piotr Tymoszuk, Judith Löffler‐Ragg, Dietmar Rieder, Zlatko Trajanoski, Anne Krogsdam, Egon Demetz, Maria Yurchenko,

Abstract

Our study combining human lung transcriptomics with functional studies in human macrophages clearly supports the design and development of TLR4 - directed therapeutics to mitigate hyperinflammation in severe COVID-19.

References

	Year	Citations

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