The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

Yingyao Zhou, Bin Zhou, Lars Pache et al. · Nature Communications · 2019 · 14.9K citations · Full text

Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression

Christoph Hafemeister, Rahul Satija · Genome biology · 2019 · 4.7K citations · Full text

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

Christopher S. McGinnis, Lyndsay M. Murrow, Zev J. Gartner · Cell Systems · 2019 · 4.2K citations · Full text

Doublet Detection, Functional Genomics, Sequencing +15

UpSetR: an R package for the visualization of intersecting sets and their properties

Jake R. Conway, Alexander Lex, Nils Gehlenborg · Bioinformatics · 2017 · 3.6K citations · Full text

MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data

Greg Finak, Andrew McDavid, Masanao Yajima et al. · Genome biology · 2015 · 3.4K citations · Full text

Engineering, Genetics, Transcriptional Changes +21