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Programmable late-stage functionalization of bridge-substituted bicyclo[1.1.1]pentane bis-boronates

Yangyang Yang, Jet Tsien, Ryan Dykstra, Si-Jie Chen, James B. Wang, Rohan R. Merchant, Jonathan M. E. Hughes, Byron K. Peters, Osvaldo Gutiérrez, Tian Qin

Nature Chemistry · 2023 · 58 citations · 64 references

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64

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

Frank Lovering, Jack Bikker, Christine Humblet · Journal of Medicinal Chemistry · 2009 · 4.4K citations

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Single-electron transmetalation in organoboron cross-coupling by photoredox/nickel dual catalysis

John C. Tellis, David N. Primer, Gary A. Molander · Science · 2014 · 1.3K citations · Full text

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Nickel-Catalyzed Cross-Coupling of Photoredox-Generated Radicals: Uncovering a General Manifold for Stereoconvergence in Nickel-Catalyzed Cross-Couplings

Osvaldo Gutiérrez, John C. Tellis, David N. Primer et al. · Journal of the American Chemical Society · 2015 · 604 citations · Full text

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Strain-release amination

Ryan Gianatassio, Justin M. Lopchuk, Jie Wang et al. · Science · 2016 · 580 citations

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Molecular Shape Diversity of Combinatorial Libraries:  A Prerequisite for Broad Bioactivity

Wolfgang Sauer, Matthias Schwarz · Journal of Chemical Information and Computer Sciences · 2003 · 496 citations

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