Concepedia

Late-stage Functionalization Planning

Late-Stage Functionalization Planning is a retrosynthetic strategy that involves the deliberate identification and functionalization of specific molecular sites in complex intermediates to enable efficient diversification late in a synthetic route, thereby minimizing redundant synthetic steps and maximizing synthetic efficiency.

29

Publications

1.3K

Citations

146

Authors

52

Institutions

Publications per year

2017–2026

25

Parents

Publications

29

Photocatalytic hydrogen atom transfer: the philosopher's stone for late-stage functionalization?

Luca Capaldo, Lorenzo L. Quadri, Davide Ravelli · Green Chemistry · 2020 · 239 citations

, , +15

Synthesis and Late-Stage Functionalization of Complex Molecules through C–H Fluorination and Nucleophilic Aromatic Substitution

Patrick S. Fier, John F. Hartwig · Journal of the American Chemical Society · 2014 · 154 citations · Full text

, , +16

Decatungstate-catalyzed radical disulfuration through direct C-H functionalization for the preparation of unsymmetrical disulfides

Jingjing Zhang, Armido Studer · Nature Communications · 2022 · 83 citations · Full text

, , +15

Bromination of Cycloparaphenylenes: Strain‐Induced Site‐Selective Bis‐Addition and Its Application for Late‐Stage Functionalization

Eiichi Kayahara, Rui Qu, Shigeru Yamago · Angewandte Chemie International Edition · 2017 · 60 citations

, , +11

Programmable late-stage functionalization of bridge-substituted bicyclo[1.1.1]pentane bis-boronates

Yangyang Yang, Jet Tsien, Ryan Dykstra et al. · Nature Chemistry · 2023 · 58 citations · Full text

, , +9

1–5 of 29

Authors

146

  1. EK
    Eiichi Kayahara

    Kyoto University, Japan

    2 publications · 81 citations

    2

    h-index

  2. MF
    Mirxan Farizyan

    University of Münster, Germany

    2 publications · 72 citations

    2

    h-index

  3. SY
    Shigeru Yamago

    Kyoto University, Japan

    2 publications · 81 citations

    2

    h-index

  4. RQ
    Rui Qu

    Kyoto University, Japan

    2 publications · 81 citations

    2

    h-index

  5. HC
    Hao Chen

    Max Planck Institute for Chemical Energy Conversion, Germany

    2 publications · 72 citations

    2

    h-index

1–5 of 146

Institutions

52

  1. University of Münster

    Münster, Germany

    3 h-index

    6 publications

    310 citations

  2. Instituto de Investigaciones Químicas

    Seville, Spain

    2 h-index

    6 publications

    243 citations

  3. Kyoto University

    Kyoto, Japan

    2 h-index

    6 publications

    243 citations

  4. Pfizer (United States)

    New York, United States

    2 h-index

    10 publications

    140 citations

  5. Kyoto University Institute for Chemical Research

    Kyoto, Japan

    2 h-index

    6 publications

    243 citations

  6. Max Planck Institute for Chemical Energy Conversion

    Mülheim, Germany

    2 h-index

    6 publications

    216 citations

  7. University of Amsterdam

    Amsterdam, The Netherlands

    1 h-index

    9 publications

    162 citations

  8. The University of Texas Southwestern Medical Center

    Dallas, United States

    1 h-index

    4 publications

    232 citations

1–8 of 52

Venues

  1. Journal of the American Chemical Society

    JACS · 4 publications · 245 citations

    4

    h-index

  2. The Journal of Organic Chemistry

    JOC · 3 publications · 45 citations

    3

    h-index

  3. Angewandte Chemie International Edition

    3 publications · 163 citations

    3

    h-index

  4. Organic Letters

    OL · 2 publications · 72 citations

    2

    h-index

  5. Angewandte Chemie

    2 publications · 36 citations

    2

    h-index

1–5