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Publication | Open Access

Delivery of Plasmid DNA by Ionizable Lipid Nanoparticles to Induce CAR Expression in T Cells

DOIFull Paper Access

36

Citations

33

References

2023

Year

Pedro Henrique Dias Moura Prazeres, Heloísa Athaydes Seabra Ferreira, Pedro Augusto Carvalho Costa, Walison da Silva, Marco Túllio Rodrigues Alves, Marshall S. Padilla, Ajay S. Thatte, Anderson K. Santos, Anderson Oliveira Lobo, Adriano de Paula Sabino,
International Journal of Nanomedicine

Abstract

Collectively, our results show that LNP-mediated delivery of pDNA is a suitable method to engineer human T cells to express CAR, which holds promise for improving the production methods and broader application of this therapy in the future.

References

YearCitations

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