Ye Che

BNT162b vaccines protect rhesus macaques from SARS-CoV-2

Annette B. Vogel, Isis Kanevsky, Ye Che et al. · Nature · 2021 · 725 citations · Full text

Vaccination, Bnt162b Vaccines, Vaccine Development +4

Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors

Mark E. Flanagan, J. A. Abramite, Dennis P. Anderson et al. · Journal of Medicinal Chemistry · 2014 · 318 citations

Combinatorial Chemistry, Drug Target, Thiol-reactive Covalent Inhibitors +17

Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2<i>S</i>,5<i>R</i>)-5-((7<i>H</i>-Pyrrolo[2,3-<i>d</i>]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans

Atli Thorarensen, Martin E. Dowty, Mary Ellen Banker et al. · Journal of Medicinal Chemistry · 2017 · 158 citations · Full text

Specific Inhibitor, Drug Target, Pharmacotherapy +25

A prefusion SARS-CoV-2 spike RNA vaccine is highly immunogenic and prevents lung infection in non-human primates

Annette B. Vogel, Isis Kanevsky, Ye Che et al. · 2020 · 138 citations · Full text

Vaccination, Vaccine Development, Prevents Lung Infection +15

Thermodynamic analysis of water molecules at the surface of proteins and applications to binding site prediction and characterization

Thijs Beuming, Ye Che, Robert Abel et al. · Proteins Structure Function and Bioinformatics · 2011 · 132 citations · Full text

Hydration Site Energetics, Protein Chemistry, Thermodynamic Analysis +13