A mouse model with high clonal barcode diversity for joint lineage, transcriptomic, and epigenomic profiling in single cells

UMAP: Uniform Manifold Approximation and Projection

Leland McInnes, John Healy, Nathaniel Saul et al. · The Journal of Open Source Software · 2018 · 9.6K citations · Full text

Computing, Computer Science, Data Visualization +12

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

Felix Krueger, Simon Andrews · Bioinformatics · 2011 · 5.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +16

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

B Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie et al. · Cell · 2006 · 5.4K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +12

Nonparametric estimation of the number of classes in a population

Anne Chao · Scandinavian Journal of Statistics · 1984 · 4.3K citations

Natural Sciences, Biostatistics, Mathematics +14

A unique chromatin signature uncovers early developmental enhancers in humans

Álvaro Rada-Iglesias, Ruchi Bajpai, Tomek Swigut et al. · Nature · 2010 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +10