Annals of the Academy of Medicine Singapore · 2004 · 330 citations · 26 references
AgricultureFood ScienceNutritional SciencesFood ChemistryFood SafetyHuman NutritionBioactive Food ComponentsTobacco UseBetel NutBetel Quid UseOral Health Epidemiology
Betel quid chewing is an ancient practice common in many countries of Asia and among migrated communities in Africa, Europe and North America. It enjoys complete social acceptance in many societies and is also popular among women. In its most basic form, betel quid consists of betel leaf (Piper betel), areca nut, the main psychoactive ingredient, and slaked lime (calcium hydroxide). Areca nut is said to be the fourth most commonly used psychoactive substance in the world, after caffeine, nicotine and alcohol. There are a great variety of ingredients and ways of preparing betel quid in different countries. In some, particularly in India, tobacco is added to the quid. In recent years, commercially-manufactured non-perishable forms of betel quid (pan masala or betel quid mixtures and gutka), not containing betel leaf, have been marketed. Within a short period of about 2 decades, this industry has risen in value to several hundred US million dollars. Use of areca nut in any form is not safe for oral health; the use of commercially manufactured forms seems even riskier.
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Global epidemiology of areca nut usage
Priti Gupta, Saman Warnakulasuriya · Addiction Biology · 2002 · 648 citations
Epidemiologic and histologic study of oral cancer and leukoplakia among 50,915 villagers in India
Fali S. Mehta, J. J. Pindborg, Priti Gupta et al. · Cancer · 1969 · 219 citations · Full text