Concepedia

Spermidine suppresses oxidative stress and ferroptosis by Nrf2/HO-1/GPX4 and Akt/FHC/ACSL4 pathway to alleviate ovarian damage

Chunyang Niu, Dongmei Jiang, Yongni Guo, Zelong Wang, Qian Sun, Xin Wang, Weikang Ling, Xiaoguang An, Chengweng Ji, Shuo Li,

Life Sciences · 2023 · 76 citations · 32 references

DOI

Concepts

References

32

Cardioprotection and lifespan extension by the natural polyamine spermidine

Tobias Eisenberg, Mahmoud Abdellatif, Sabrina Schroeder et al. · Nature Medicine · 2016 · 1.1K citations · Full text

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Protective mechanism of FSH against oxidative damage in mouse ovarian granulosa cells by repressing autophagy

Ming Shen, Yi Jiang, Zhiqiang Guan et al. · Autophagy · 2017 · 233 citations · Full text

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Dietary spermidine improves cognitive function

Sabrina Schroeder, Sebastian J. Hofer, Andreas Zimmermann et al. · Cell Reports · 2021 · 214 citations · Full text

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Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice

Z-H Song, Haiyan Yu, Ping Wang et al. · Cell Death and Disease · 2015 · 172 citations · Full text

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Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline

Claudia Schwarz, Slaven Stekovic, Miranka Wirth et al. · Aging · 2018 · 159 citations · Full text

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