Concepedia

Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir

Yinkai Duan, Hao Zhou, Xiang Liu, Sho Iketani, Meng-Meng Lin, Xiaoyu Zhang, Qucheng Bian, Haofeng Wang, Haoran Sun, Seo Jung Hong,

Nature · 2023 · 174 citations · 34 references

Concepts

Life SciencesInfectious DiseasesMolecular BiologyMolecular PharmacologyMolecular VirologyVirologyAntiviral AgentsAntiviral Drug ResistanceAntiviral PharmacologyAntiviral ResistanceViral GeneticsViral InfectionsAntiviral Resistance MechanismsAntiviral Signaling PathwaysResistance PathwaysSars-cov-2 Antiviral ResistanceStructural Basis Of Resistance

References

34

Features and development of <i>Coot</i>

Paul Emsley, Bernhard Lohkamp, W. G. Scott et al. · Acta Crystallographica Section D Biological Crystallography · 2010 · 29.6K citations · Full text

Natural Sciences, Chemistry, Biomolecular Modeling +16

<i>Phaser</i>crystallographic software

Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al. · Journal of Applied Crystallography · 2007 · 20.9K citations · Full text

Natural Sciences, Chemistry, Computational Chemistry +16

Wolfgang Kabsch · Acta Crystallographica Section D Biological Crystallography · 2010 · 16.9K citations · Full text

Computing, Computer Science, Computational Geometry +13

Towards automated crystallographic structure refinement with <i>phenix.refine</i>

Pavel V. Afonine, Ralf W. Grosse‐Kunstleve, Nathaniel Echols et al. · Acta Crystallographica Section D Biological Crystallography · 2012 · 5.7K citations · Full text

Natural Sciences, Chemistry, Computational Chemistry +15

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

Zhenming Jin, Xiaoyu Du, Yechun Xu et al. · Nature · 2020 · 4.5K citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +10