Mendelian randomization analyses identify bidirectional causal relationships of obesity with psychiatric disorders

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Theo Vos, Amanuel Alemu Abajobir, Kalkidan Hassen Abate et al. · The Lancet · 2017 · 13.5K citations · Full text

Public Health, Health Sciences, Epidemiologic Methods +16

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

Jack Bowden, George Davey Smith, Stephen Burgess · International Journal of Epidemiology · 2015 · 10.6K citations · Full text

Public Health, Biostatistics, Genetics +15

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Marie Verbanck, Chia‐Yen Chen, Benjamin M. Neale et al. · Nature Genetics · 2018 · 9.2K citations

Public Health, Biostatistics, Genetics +12

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

Stephen Burgess, Adam S. Butterworth, Simon G. Thompson · Genetic Epidemiology · 2013 · 6.4K citations · Full text

Life Sciences, Biostatistics, Genetics +15

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

Debbie A. Lawlor, Roger Harbord, Jonathan A C Sterne et al. · Statistics in Medicine · 2007 · 5K citations

Public Health, Biostatistics, Genetics +15