Concepedia

Bidirectional Mendelian Randomization

Bidirectional Mendelian Randomization is a methodological framework within genetic epidemiology that extends standard Mendelian randomization by enabling the simultaneous assessment of causal effects in both directions between two traits or exposures, thereby distinguishing primary causal relationships from reverse causation using genetic instruments.

344

Publications

12.4K

Citations

2.5K

Authors

792

Institutions

Publications per year

2017–2026

341

Parents

Publications

344

Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis

Jianfeng Lin, Jiawei Zhou, Yan Xu · Brain · 2023 · 271 citations · Full text

, , +13

Type 2 Diabetes and Hypertension

Dianjianyi Sun, Tao Zhou, Yoriko Heianza et al. · Circulation Research · 2019 · 263 citations · Full text

, , +15

No Genetic Causal Association Between Periodontitis and Arthritis: A Bidirectional Two-Sample Mendelian Randomization Analysis

Kang-Jia Yin, Ji-Xiang Huang, Peng Wang et al. · Frontiers in Immunology · 2022 · 212 citations · Full text

, , +17

Assessment of Causal Direction Between Gut Microbiota–Dependent Metabolites and Cardiometabolic Health: A Bidirectional Mendelian Randomization Analysis

Jinzhu Jia, Dou Pan, Meng Gao et al. · Diabetes · 2019 · 192 citations

, , +14

Assessing the Causal Relationships Between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization

Natalie McCormick, Mark J. O’Connor, Chio Yokose et al. · Arthritis & Rheumatology · 2021 · 166 citations · Full text

, , +17

1–5 of 344

Authors

2.5K

  1. GD
    George Davey Smith

    University of Bristol, United Kingdom

    10 publications · 533 citations

    10

    h-index

  2. MR
    Marcus R. Munafò

    University of Bristol, United Kingdom

    9 publications · 521 citations

    9

    h-index

  3. TH
    Tao Huang

    Peking University, China

    6 publications · 136 citations

    6

    h-index

  4. SB
    Stephen Burgess

    University of Cambridge, United Kingdom

    5 publications · 222 citations

    5

    h-index

  5. HS
    Hannah Sallis

    University of Bristol, United Kingdom

    5 publications · 282 citations

    5

    h-index

1–5 of 2.5K

Institutions

792

  1. University of Bristol

    Bristol, United Kingdom

    19 h-index

    101 publications

    5.7K citations

  2. Central South University

    Changsha, China

    15 h-index

    101 publications

    3.1K citations

  3. Shanghai Jiao Tong University

    Shanghai, China

    15 h-index

    101 publications

    3.8K citations

  4. Peking University

    Beijing, China

    14 h-index

    67 publications

    3K citations

  5. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    14 h-index

    55 publications

    2.4K citations

  6. Jilin University

    Changchun, China

    13 h-index

    83 publications

    1.9K citations

  7. University of Hong Kong

    Pok Fu Lam, Hong Kong

    12 h-index

    18 publications

    956 citations

  8. Harvard University

    Cambridge, United States

    12 h-index

    75 publications

    5.1K citations

1–8 of 792

Venues

  1. Frontiers in Immunology

    31 publications · 1.2K citations

    21

    h-index

  2. Frontiers in Endocrinology

    16 publications · 315 citations

    14

    h-index

  3. Frontiers in Genetics

    14 publications · 263 citations

    13

    h-index

  4. Frontiers in Microbiology

    12 publications · 291 citations

    12

    h-index

  5. Scientific Reports

    9 publications · 233 citations

    9

    h-index

1–5