Concepedia

Branched-chain amino acids promote thrombocytopoiesis by activating mTOR signaling

Haojie Jiang, Lin Zhang, Mina Yang, Guoming Li, Chen Ding, Min Xin, Jing Dai, Xueqing Sun, Xuemei Fan, Haipeng Sun,

Journal of Thrombosis and Haemostasis · 2023 · 18 citations · 19 references

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19

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance

Cholsoon Jang, Sungwhan F. Oh, Shogo Wada et al. · Nature Medicine · 2016 · 586 citations · Full text

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Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure

Haipeng Sun, Kristine C. Olson, Chen Gao et al. · Circulation · 2016 · 536 citations · Full text

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The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase

Phillip J. White, Robert W. McGarrah, Paul A. Grimsrud et al. · Cell Metabolism · 2018 · 352 citations · Full text

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Mutations in <i>BCKD-kinase</i> Lead to a Potentially Treatable Form of Autism with Epilepsy

Gaia Novarino, Paul El-Fishawy, Hülya Kayserili et al. · Science · 2012 · 312 citations · Full text

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Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression

Russell Ericksen, Siew Lay Lim, Eoin McDonnell et al. · Cell Metabolism · 2019 · 291 citations · Full text

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