Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure

Haipeng Sun, Kristine C. Olson, Chen Gao, +20

Circulation

Defective Branched-Chain Amino Acid Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-Reperfusion Injury

Tao Li, Zhen Zhang, Stephen C. Kolwicz, +10

Cell Metabolism

Metabolic SyndromeHeart FailureEnergy MetabolismBiochemistryReperfusion Injury +9

Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance

Meiyi Zhou, Jing Shao, Cheng‐Yang Wu, +17

Diabetes

Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells

Gang Lü, Haipeng Sun, Pengxiang She, +7

Journal of Clinical Investigation

MitophagyAmino AcidsCellular PhysiologyProtein SynthesisOxidative Stress +20

Klf15 Orchestrates Circadian Nitrogen Homeostasis

Darwin Jeyaraj, Frank A. J. L. Scheer, Jürgen A. Ripperger, +18

Cell Metabolism

Plant Circadian ClockAlertnessMedicinePhysiologyHomeostatic Mechanism +7

Translational Control of Nrf2 Protein in Activation of Antioxidant Response by Oxidants

Sally E. Purdom-Dickinson, Haipeng Sun, Qin M. Chen

Molecular Pharmacology

MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury

Qingqing Wei, Haipeng Sun, Shuwei Song, +10

Journal of Clinical Investigation

Branched-Chain Amino Acid Catabolism Promotes Thrombosis Risk by Enhancing Tropomodulin-3 Propionylation in Platelets

Yanyan Xu, Haojie Jiang, Li Li, +13

Circulation

Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy

Mingming Zhao, Haoran Wei, Chenze Li, +19

Nature Communications

Involvement of the Hippo pathway in regeneration and fibrogenesis after ischaemic acute kidney injury: YAP is the key effector

Jing Xu, Pei-Xue Li, Jun Wu, +17

Clinical Science

Hippo Pathway ComponentsRenal PathologyRenal InflammationCellular PhysiologyRenal Function +15