Concepedia

DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK1 − TRAF3 complex

Yanwei Zhang, Jing Cen, Gaoliang Yuan, Kangyong Chen, Wa Gao, Jing Chen, Mikołaj Adamek, Zhiying Jia, Jun Zou

Cellular and Molecular Life Sciences · 2023 · 19 citations · 51 references

DOIFull text

Open access

Concepts

References

51

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa et al. · Nature Immunology · 2004 · 3.9K citations

, , +16

Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

Rashu B. Seth, Lijun Sun, Chee-Kwee Ea et al. · Cell · 2005 · 3.3K citations · Full text

, , +10

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Taro Kawai, Ken Takahashi, Shintaro Sato et al. · Nature Immunology · 2005 · 2.5K citations

, , +12

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

Etienne Meylan, Joseph Curran, Kay Hofmann et al. · Nature · 2005 · 2.4K citations · Full text

, , +13

VISA Is an Adapter Protein Required for Virus-Triggered IFN-β Signaling

Liang‐Guo Xu, Yan‐Yi Wang, Ke-Jun Han et al. · Molecular Cell · 2005 · 1.8K citations · Full text

, , +14