Concepedia

Publication | Open Access

Novel hydroxamic acid derivative induces apoptosis and constrains autophagy in leukemic cells

DOIFull Paper Access

17

Citations

51

References

2023

Year

Marten A. Fischer, Al‐Hassan M. Mustafa, Kristin Hausmann, Ramy Ashry, Anita G. Kansy, Magdalena C. Liebl, Christina Brachetti, Andrea Piée‐Staffa, Matthes Zessin, Hany S. Ibrahim,
Journal of Advanced Research

Abstract

These data reveal that HDACs are required to stabilize autophagy proteins through suppression of apoptosis in leukemic cells. HDAC3 appears as a valid anti-cancer target for pharmacological intervention.

References

YearCitations

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