Concepedia

Chronic Stress Exposure Alters the Gut Barrier: Sex-Specific Effects on Microbiota and Jejunum Tight Junctions

Ellen Doney, Laurence Dion‐Albert, François Coulombe-Rozon, Natasha Osborne, Renaud Bernatchez, Sam E.J. Paton, Fernanda Neutzling Kaufmann, Roseline Olory Agomma, José L. Solano, Raphael Gaumond,

Biological Psychiatry Global Open Science · 2023 · 18 citations · 66 references

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Abstract

Our results provide evidence that chronic stress disrupts intestinal barrier homeostasis in conjunction with the manifestation of depressive-like behaviors in a sex-specific manner in mice and, possibly, in human depression.

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