Evaluation of RNAi therapeutics VIR-2218 and ALN-HBV for chronic hepatitis B: Results from randomized clinical trials

EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection

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Hepatitis D, Viral Hepatitis, Hepatitis B +5

Multivalent <i>N</i>-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

Jayaprakash K. Nair, Jennifer L. S. Willoughby, Amy Chan et al. · Journal of the American Chemical Society · 2014 · 1K citations

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor

Adrien Decorsière, H. Mueller, Pieter C. Van Breugel et al. · Nature · 2016 · 520 citations

Host Restriction Factor, Host Factor, Molecular Virology +10

RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg

Christine I. Wooddell, Man‐Fung Yuen, Henry Lik‐Yuen Chan et al. · Science Translational Medicine · 2017 · 477 citations · Full text

High antigen levels are the cause of T cell exhaustion during chronic viral infection

Scott N. Mueller, Rafi Ahmed · Proceedings of the National Academy of Sciences · 2009 · 395 citations · Full text

High Antigen Levels, Mhc Class, Adaptive Immune System +17