Concepedia

Divergent electrosynthesis of 3-iodoindoles and indoles from 2-ethynylanilines under ambient and aqueous conditions

Binbin Huang, Guiling Chen, Haoxiang Zhang, Xinye Tang, Jiawei Yuan, Caicai Lu, Junlei Wang

Organic Chemistry Frontiers · 2023 · 34 citations · 28 references

DOI

Concepts

Abstract

A mild and simple electrochemical system has been developed for the efficient cyclization of 2-ethynylanilines to selectively access 3-iodoindoles or indoles.

References

28

Organic electrosynthesis: a promising green methodology in organic chemistry

Bernardo A. Frontana‐Uribe, R. Daniel Little, Jorge G. Ibáñez et al. · Green Chemistry · 2010 · 1.2K citations

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IPy<sub>2</sub>BF<sub>4</sub>‐Promoted Intramolecular Addition of Masked and Unmasked Anilines to Alkynes: Direct Assembly of 3‐Iodoindole Cores

José Barluenga, Mónica Trincado, Eduardo Rubio et al. · Angewandte Chemie International Edition · 2003 · 299 citations · Full text

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Development of an Efficient Procedure for Indole Ring Synthesis from 2-Ethynylaniline Derivatives Catalyzed by Cu(II) Salts and Its Application to Natural Product Synthesis

Kou Hiroya, Shin Itoh, Takao Sakamoto · The Journal of Organic Chemistry · 2004 · 261 citations

, , +15

Electrochemical C−H/N−H Functionalization for the Synthesis of Highly Functionalized (Aza)indoles

Zhong‐Wei Hou, Zhong‐Yi Mao, Huaibo Zhao et al. · Angewandte Chemie International Edition · 2016 · 250 citations

, , +16

Ruthenium-Catalyzed Electrochemical Dehydrogenative Alkyne Annulation

Fan Xu, Yanjie Li, Chong Huang et al. · ACS Catalysis · 2018 · 222 citations · Full text

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