Concepedia

Cancer cell-autonomous cGAS-STING response confers drug resistance

Qian-Ming Lv, Hui-Min Lei, Shiyi Wang, Keren Zhang, Ya‐Bin Tang, Ying Shen, Liming Lu, Hongzhuan Chen, Liang Zhu

Cell chemical biology · 2023 · 20 citations · 18 references

DOI

Concepts

References

18

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

Sreenath V. Sharma, Diana Lee, Bihua Li et al. · Cell · 2010 · 2.8K citations · Full text

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Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv et al. · Nature · 2017 · 2K citations · Full text

, , +16

Chromosomal instability drives metastasis through a cytosolic DNA response

Samuel F. Bakhoum, Bryan Ngo, Ashley M. Laughney et al. · Nature · 2018 · 1.6K citations

, , +14

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

Leticia Corrales, Laura Hix Glickman, Sarah M. McWhirter et al. · Cell Reports · 2015 · 1.5K citations · Full text

, , +17

Targeting STING with covalent small-molecule inhibitors

Simone M. Haag, Muhammet F. Gülen, Luc Reymond et al. · Nature · 2018 · 1.1K citations · Full text

, , +12