Concepedia

Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis

Xiaomei Yang, Xiaoqi Wang, Li-Peng Hu, Mingxuan Feng, Yaoqi Zhou, Dongxue Li, Jun Li, Xiao-Cao Miao, Yanli Zhang, Linli Yao,

Gastroenterology · 2023 · 26 citations · 34 references

DOIFull text

Open access

Concepts

References

34

Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma

Augusto Villanueva, Derek Y. Chiang, Pippa Newell et al. · Gastroenterology · 2008 · 728 citations · Full text

, , +17

Inducing and exploiting vulnerabilities for the treatment of liver cancer

Cun Wang, Serena Vegna, Haojie Jin et al. · Nature · 2019 · 430 citations

, , +4

Stress- and ubiquitylation-dependent phase separation of the proteasome

Sayaka Yasuda, Hikaru Tsuchiya, Ai Kaiho et al. · Nature · 2020 · 323 citations

, , +12

A Targeting Modality for Destruction of RNA Polymerase I that Possesses Anticancer Activity

Karita Peltonen, Laureen Colis, Hester Liu et al. · Cancer Cell · 2014 · 318 citations · Full text

, , +13

A non-canonical DNA structure is a binding motif for the transcription factor SP1 in vitro

Eun‐Ang Raiber, Ramon Kranaster, Enid Y.N. Lam et al. · Nucleic Acids Research · 2011 · 249 citations · Full text

, , +17