Massively parallel base editing to map variant effects in human hematopoiesis

Salmon provides fast and bias-aware quantification of transcript expression

Rob Patro, Geet Duggal, Michael I. Love et al. · Nature Methods · 2017 · 13.7K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +12

SCANPY: large-scale single-cell gene expression data analysis

F. Alexander Wolf, Philipp Angerer, Fabian J. Theis · Genome biology · 2018 · 9.3K citations · Full text

Life Sciences, Bioinformatics, Cell Biology +15

Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

Shikshya Shrestha, Steven M. Offer · Medical Epigenetics · 2016 · 9K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

Jian Ye, George Coulouris, Irena Zaretskaya et al. · BMC Bioinformatics · 2012 · 6.2K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +12

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor, Y. Bill Kim, Michael S. Packer et al. · Nature · 2016 · 5.4K citations · Full text

Life Sciences, Genetics, Molecular Biology +9