Concepedia

In silico Study of Antiviral Activity of Polyphenol Compounds from Ocimum basilicum by Molecular Docking, ADMET, and Drug-Likeness Analysis

Dikdik Kurnia, Salsabila Aqila Putri, Sefren Geiner Tumilaar, Achmad Zainuddin, Hendra Dian Adhita Dharsono, Meiny Faudah Amin

Advances and Applications in Bioinformatics and Chemistry · 2023 · 28 citations · 35 references

DOIFull text

Open access

Abstract

Based on the data obtained, Apigenin-7-glucuronide and dihydrokaempferol-3-glucoside are compounds that have more potential to have an antiviral effect on the main protease enzyme than aesculetin. Based on pharmacokinetic parameters and drug-likeness, three compounds can be used as lead compounds for further research.

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