Artesunate ameliorates irinotecan-induced intestinal injury by suppressing cellular senescence and significantly enhances anti-tumor activity

The TSC-mTOR pathway regulates macrophage polarization

Vanessa Byles, Anthony J. Covarrubias, Issam Ben‐Sahra et al. · Nature Communications · 2013 · 608 citations · Full text

Signal Transduction, Signaling Pathway, Cell Signaling +7

Phase III Trial of Irinotecan/Cisplatin Compared With Etoposide/Cisplatin in Extensive-Stage Small-Cell Lung Cancer: Clinical and Pharmacogenomic Results From SWOG S0124

Primo N. Lara, Ronald B. Natale, John Crowley et al. · Journal of Clinical Oncology · 2009 · 517 citations · Full text

TORC1 inhibition enhances immune function and reduces infections in the elderly

Joan B. Mannick, Melody K. Morris, Hans Hockey et al. · Science Translational Medicine · 2018 · 463 citations

<scp>AMPK</scp> activation protects cells from oxidative stress‐induced senescence via autophagic flux restoration and intracellular <scp>NAD</scp> ⁺ elevation

Xiaojuan Han, Haoran Tai, Xiaobo Wang et al. · Aging Cell · 2016 · 291 citations · Full text

Prevention of irinotecan induced diarrhea by probiotics: A randomized double blind, placebo controlled pilot study

Michal Mego, Jozef Chovanec, Iveta Vochyanova-Andrezalova et al. · Complementary Therapies in Medicine · 2015 · 222 citations

Probiotic, Dysbiosis, Medicine +7