Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence

Haoran Tai, Zhe Wang, Hui Gong, +13

Autophagy

MitophagyAgingMitochondrial DysfunctionGeneticsCell Death +14

<scp>AMPK</scp> activation protects cells from oxidative stress‐induced senescence via autophagic flux restoration and intracellular <scp>NAD</scp> ⁺ elevation

Xiaojuan Han, Haoran Tai, Xiaobo Wang, +12

Aging Cell

FTO is required for myogenesis by positively regulating mTOR-PGC-1α pathway-mediated mitochondria biogenesis

Xiaobo Wang, Ning Huang, Min Yang, +10

Cell Death and Disease

miR-146a impedes the anti-aging effect of AMPK via NAMPT suppression and NAD+/SIRT inactivation

Hui Gong, Honghan Chen, Peng Xiao, +13

Signal Transduction and Targeted Therapy

Autolysosomal degradation of cytosolic chromatin fragments antagonizes oxidative stress–induced senescence

Xiaojuan Han, Honghan Chen, Hui Gong, +10

Journal of Biological Chemistry

Fat mass and obesity-associated protein attenuates lipid accumulation in macrophage foam cells and alleviates atherosclerosis in apolipoprotein E-deficient mice

Chunfen Mo, Ming Yang, Xiaojuan Han, +5

Journal of Hypertension

Nrf2-SHP Cascade-Mediated STAT3 Inactivation Contributes to AMPK-Driven Protection Against Endotoxic Inflammation

Hui Gong, Haoran Tai, Ning Huang, +14

Frontiers in Immunology

Combined use of bFGF/EGF and all-trans-retinoic acid cooperatively promotes neuronal differentiation and neurite outgrowth in neural stem cells

Haixia Zhao, Xuan Zuo, Liyi Ren, +12

Neuroscience Letters

Regenerative MedicineNeurite OutgrowthNeuroregenerationDevelopmental BiologyAll-trans-retinoic Acid +12

Protein kinase Cβ activates fat mass and obesity‐associated protein by influencing its ubiquitin/proteasome degradation

Haoran Tai, Xiaobo Wang, Jiao Zhou, +10

The FASEB Journal

Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy

Jiao Zhou, Honghan Chen, Jintao Du, +7

Frontiers in Pharmacology