Crosstalk between microglia and neural stem cells influences the relapse of glioblastoma in GBM immunological microenvironment

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.7K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus

Carolyn J. Brown, Brian Hendrich, Jim L. Rupert et al. · Cell · 1992 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +10

Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma

Spyros Darmanis, Steven A. Sloan, Derek Croote et al. · Cell Reports · 2017 · 1.1K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq

Andrew S. Venteicher, Itay Tirosh, Christine Hebert et al. · Science · 2017 · 1.1K citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

Sören Müller, Gary Kohanbash, Siyuan Liu et al. · Genome biology · 2017 · 679 citations · Full text

Medicine, Neurobiology, Oncology +17