Concepedia

The role of protein arginine deiminase 4-dependent neutrophil extracellular traps formation in ulcerative colitis

Ping Wang, Dan Liu, Ziqi Zhou, Fangjun Liu, Yiming Shen, Qi You, Shiping Lu, Jie Wu

Frontiers in Immunology · 2023 · 33 citations · 30 references

DOIFull text

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Abstract

This study provided a research basis for the role of PAD4-mediated NETs formation in the pathogenesis of UC and suggested that inhibition of PAD4 activity and the formation of NETs may be helpful for the prevention and treatment of UC.

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