Concepedia

An inhibitor with GSK3β and DYRK1A dual inhibitory properties reduces Tau hyperphosphorylation and ameliorates disease in models of Alzheimer's disease

Xin Liu, Lingyun Lai, Jiang-xia Chen, Xiang Li, Nan Wang, Lijun Zhou, Xiaowen Jiang, Xiaolong Hu, Xinming Jiao, Zhentong Qi,

Neuropharmacology · 2023 · 28 citations · 24 references

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Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

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Structural Insights and Biological Effects of Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418

Ratan V. Bhat, Yafeng Xue, Stefan von Berg et al. · Journal of Biological Chemistry · 2003 · 550 citations · Full text

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Plasma p‐tau181, p‐tau217, and other blood‐based Alzheimer's disease biomarkers in a multi‐ethnic, community study

Adam M. Brickman, Jennifer J. Manly, Lawrence S. Honig et al. · Alzheimer s & Dementia · 2021 · 381 citations · Full text

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Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow

Chenglong Xie, Xu‐Xu Zhuang, Zhangming Niu et al. · Nature Biomedical Engineering · 2022 · 340 citations · Full text

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The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimer’s disease

Niklas Lonnemann, Shirin Hosseini, Carlo Marchetti et al. · Proceedings of the National Academy of Sciences · 2020 · 293 citations · Full text

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