Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma - Concepedia

Concepedia

Publication | Open Access

Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma

DOI Full Paper Access

18

Citations

68

References

2023

Year

Cristina Di Giorgio, Rachele Bellini, Antonio Lupia, Carmen Massa, Martina Bordoni, Silvia Marchianò, Rosalinda Rosselli, Valentina Sepe, Pasquale Rapacciuolo, Federica Moraca,

Frontiers in Oncology

Abstract

BAR502 reverses the pattern LIF-induced in a FXR and GPBAR1 independent manner, suggesting a potential role for BAR502 in the treatment of LIFR overexpressing-PDAC.

References

	Year	Citations

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