Monitoring multiple myeloma by idiotype-specific peptide binders of tumor-derived exosomes

Enrico Iaccino, Selena Mimmi, Vincenzo Dattilo, +13

Molecular Cancer

Indole and 2,4-Thiazolidinedione conjugates as potential anticancer modulators

Domenica Corigliano, Riyaz Syed, Sebastiano Messineo, +10

PeerJ

A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors

Giosuè Costa, Fabrizio Carta, Francesca Alessandra Ambrosio, +12

European Journal of Medicinal Chemistry

Medicinal ChemistryBioorganic ChemistryBiochemistryNatural SciencesMedicine +7

Computer-based techniques for lead identification and optimization I: Basics

Annalisa Maruca, Francesca Alessandra Ambrosio, Antonio Lupia, +9

Physical Sciences Reviews

Lead ConversionDrug TargetEngineeringHit IdentificationLead Identification +26

Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives

Raffaella Catalano, Federica Moraca, Jussara Amato, +14

European Journal of Medicinal Chemistry

EngineeringIndolo-naphthyridine Scaffold DerivativesBiological EvaluationsBioconjugationOligonucleotide +4

Molecular modelling of epitopes recognized by neoplastic B lymphocytes in Chronic Lymphocytic Leukemia

Antonio Lupia, Selena Mimmi, Enrico Iaccino, +9

European Journal of Medicinal Chemistry

Neoplastic BLymphoid NeoplasiaHematological MalignancySystems BiologyChronic Lymphocytic Leukemia +8

Ligand-based drug repurposing strategy identified SARS-CoV-2 RNA G-quadruplex binders

Federica Moraca, Simona Marzano, Francesco D’Amico, +9

Chemical Communications

Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma

Cristina Di Giorgio, Rachele Bellini, Antonio Lupia, +16

Frontiers in Oncology

Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors

Annalisa Maruca, Delia Lanzillotta, Roberta Rocca, +9

Molecules

Drug TargetHit IdentificationKinase InhibitorsMedicinal ChemistryBioactive Compounds +14

Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma

Cristina Di Giorgio, Antonio Lupia, Silvia Marchianò, +14

Cells

OncologyPotent Lifr AntagonistPancreatic CancerMedicineImmunology +12