Silvia Marchianò

The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

Michele Biagioli, Adriana Carino, Sabrina Cipriani et al. · The Journal of Immunology · 2017 · 326 citations

Life Sciences, Immunology, Pharmacology +17

BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis

Adriana Carino, Sabrina Cipriani, Silvia Marchianò et al. · Scientific Reports · 2017 · 124 citations · Full text

Medicine, Endocrinology, Pharmacology +17

Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

Adriana Carino, Federica Moraca, Bianca Fiorillo et al. · Frontiers in Chemistry · 2020 · 106 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH

Adriana Carino, Michele Biagioli, Silvia Marchianò et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2019 · 72 citations

Life Sciences, Nutritional Sciences, Pharmacology +17

GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis

Michele Biagioli, Adriana Carino, Chiara Fiorucci et al. · Cellular and Molecular Gastroenterology and Hepatology · 2019 · 67 citations · Full text

Life Sciences, Immunology, Pharmacology +15