Concepedia

Publication | Open Access

AMPK Phosphorylates ZDHHC13 to Increase MC1R Activity and Suppress Melanomagenesis

DOIFull Paper Access

22

Citations

42

References

2023

Year

Yu Sun, Xin Li, Chengqian Yin, Judy Zhang, Ershang Liang, Xianfang Wu, Ying Ni, Joshua Arbesman, Colin R. Goding, Shuyang Chen
Cancer Research

Abstract

Phosphorylation of ZDHHC13 by AMPK at S208 promotes MC1R activation and suppresses melanocyte transformation, indicating activation of AMPK as a potential approach to prevent melanoma in people with red hair.

References

YearCitations

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