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Immunogenicity/Hypersensitivity of Biologics

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Immunocytochemical Technique, Immunodeficiencies, Immunology +16

Preclinical development of monoclonal antibodies

Kathryn Chapman, Nick Pullen, Lee Coney et al. · mAbs · 2009 · 95 citations · Full text

Immunology, Mab Development, Immunotherapy +17

The design of chronic toxicology studies of monoclonal antibodies: Implications for the reduction in use of non-human primates

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Autoimmune Disease, Immunotoxicology, Medicine +12

Species selection for nonclinical safety assessment of drug candidates: Examples of current industry practice

Rostam Namdari, Keith Jones, Samuel S. Chuang et al. · Regulatory Toxicology and Pharmacology · 2021 · 61 citations · Full text

Toxicology Species/humans, Toxicology Testing, Human Risk Assessment +19

Safety evaluation of biological drugs: What are toxicology studies in primates telling us?

Paul Baldrick · Regulatory Toxicology and Pharmacology · 2010 · 46 citations

Drug Safety, Preclinical Drug Evaluation, Pharmacology +7