Immuno · 2022 · 24 citations · 93 references
Life SciencesImmunologyNutritional SciencesEpilepsyImmunoregulationNutritional ImmunologyImmune Cell PhysiologyImmunonutrition In Clinical CareImmunosuppressionKetogenic Diet TherapyNutritional Modulation Of CytokinesTherapeutic DietsKetogenic Diet For EpilepsyNutrient-immune InteractionsNutritional ImmunosuppressionNutritional Modulation Of Immunity
Interceding nutrients have been acquiring increased attention and prominence in the field of healing and deterrence of various disorders. In this light, the present article encompasses several facets of ketogenic diet as an immunomodulator with respect to its expansive clinical applications. Accordingly, several scientific records, models, and case histories, including viral infections, cancer, chronic diseases, e.g., cardiovascular diseases, epilepsy, as well as numerous other neuro-disorders, are assembled, revealing a profound influence of KD in favor of improvement in the patient’s condition. We accentuate possible manifold mechanisms of KD that require further exploration.
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NF-κB signaling in inflammation
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Life Sciences, Immunology, Pathology +17
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
Peter Duewell, Hajime Kono, Katey J. Rayner et al. · Nature · 2010 · 3.9K citations · Full text
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
Yun‐Hee Youm, Kim Nguyen, Ryan W. Grant et al. · Nature Medicine · 2015 · 2.1K citations · Full text
The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet
C. Anders Olson, Helen E. Vuong, Jessica M. Yano et al. · Cell · 2018 · 1.1K citations