Concepedia

mTOR inhibitor, gemcitabine and PD-L1 antibody blockade combination therapy suppresses pancreatic cancer progression via metabolic reprogramming and immune microenvironment remodeling in Trp53flox/+LSL-KrasG12D/+Pdx-1-Cre murine models

Jiangdong Qiu, Mengyu Feng, Gang Yang, Zhe Cao, Yueze Liu, Lei You, Taiping Zhang

Cancer Letters · 2022 · 45 citations · 23 references

DOI

Concepts

References

23

Cancer statistics, 2022

Rebecca L. Siegel, Kimberly D. Miller, Hannah E. Fuchs et al. · CA A Cancer Journal for Clinicians · 2022 · 18.2K citations · Full text

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Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

Lola Rahib, Benjamin D. Smith, Rhonda Aizenberg et al. · Cancer Research · 2014 · 7.3K citations

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Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

Chih‐Hao Chang, Jonathan D. Curtis, Leonard B. Maggi et al. · Cell · 2013 · 2.2K citations · Full text

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Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy

Weiyi Peng, Jie Qing Chen, Chengwen Liu et al. · Cancer Discovery · 2015 · 1.5K citations · Full text

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Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

Ping‐Chih Ho, Jessica Bihuniak, Andrew N. Macintyre et al. · Cell · 2015 · 1.4K citations · Full text

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