mSystems · 2022 · 21 citations · 29 references
Life SciencesMicrobiologyNutritionBioenergeticsMetabolismMicrobial MetabolismBacterial MetabolismGut MicrobiotaLactic Acid BacteriaBacteriostatic ActivityIntestinal Stem CellsPrebiotic MechanismsSuccinate Metabolism
In our previous study, Lactobacillus salivarius and Lactobacillus agilis were demonstrated to regulate intestinal stem cell activity in hens, but their active ingredients and the underlying mechanism remain unclear. In this study, L. salivarius supernatant was shown to directly promote intestinal stem cell activity.
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Identification of stem cells in small intestine and colon by marker gene Lgr5
Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.7K citations
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
Bryce W. Carey, Lydia W.S. Finley, Justin R. Cross et al. · Nature · 2014 · 995 citations
Intestinal label-retaining cells are secretory precursors expressing Lgr5
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The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites
Gerard E. Kaiko, Hyunji Ryu, Olivia I. Koues et al. · Cell · 2016 · 723 citations · Full text
Life Sciences, Biology, Cell Biology +14