Discovery of 1-hydroxy-2-methylquinolin-4(1H)-one derivatives as new cytochrome bd oxidase inhibitors for tuberculosis therapy

Global tuberculosis report (2014)

L.A. Gabbasova, E.R. Experts Who · 2014 · 13.2K citations

Public Health, Infectious Diseases, Microbiology +12

A Diarylquinoline Drug Active on the ATP Synthase of <i>Mycobacterium tuberculosis</i>

Koen Andries, Peter Verhasselt, Jérôme Guillemont et al. · Science · 2004 · 2.2K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis

Kévin Pethe, Pablo Bifani, Jichan Jang et al. · Nature Medicine · 2013 · 614 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Diarylquinolines target subunit c of mycobacterial ATP synthase

Anil Koul, Najoua Dendouga, Karen Vergauwen et al. · Nature Chemical Biology · 2007 · 548 citations · Full text

Life Sciences, Biochemistry, Microbiology +10

Randomized Pilot Trial of Eight Weeks of Bedaquiline (TMC207) Treatment for Multidrug-Resistant Tuberculosis: Long-Term Outcome, Tolerability, and Effect on Emergence of Drug Resistance

Andreas H. Diacon, Peter R. Donald, Alexander S. Pym et al. · Antimicrobial Agents and Chemotherapy · 2012 · 380 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +13