Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas

<i>IDH1</i>and<i>IDH2</i>Mutations in Gliomas

Hai Yan, D. Williams Parsons, Genglin Jin et al. · New England Journal of Medicine · 2009 · 5.8K citations · Full text

An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

Dan Rohle, Janeta Popovici-Müller, Nicolaos Palaskas et al. · Science · 2013 · 1.1K citations · Full text

Cancer Biology, Glioma, Tumor Biology +16

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq

Andrew S. Venteicher, Itay Tirosh, Christine Hebert et al. · Science · 2017 · 1K citations · Full text

Tumor Subclasses, Engineering, Genetics +20

Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial

Martin J. van den Bent, D Afra, Olivier De Witte et al. · The Lancet · 2005 · 1K citations

Neuro-oncology, Eortc 22845, Treatment Strategies +10

CGCG clinical practice guidelines for the management of adult diffuse gliomas

Tao Jiang, Ying Mao, Wenbin Ma et al. · Cancer Letters · 2016 · 647 citations · Full text

Neuro-oncology, Radiation Oncology, Clinical Neurosurgery +15