Identification and Analysis of Immune-Related Gene Signature in Hepatocellular Carcinoma

Abstract

Through the comprehensive analysis, we constructed an immune-related prognosis model to predict the survival of HCC patients. In addition to predicting the survival time of HCC patients, this model significantly correlates with the tumor microenvironment. Furthermore, we concluded that these ten immune-related genes (<i>BIRC5</i>, <i>CDK4</i>, <i>DCK</i>, <i>HSPA4</i>, <i>HSP90AA1</i>, <i>PSMD2</i>, <i>IL1RN</i>, <i>PGF</i>, <i>SPP1</i>, and <i>STC2</i>) serve as novel targets for antitumor immunity. Therefore, this study plays a significant role in exploring the clinical application of immune-related genes.