Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

Pornpimol Charoentong, Francesca Finotello, Mihaela Angelova, +5

Cell Reports

Machine LearningGenomic LandscapesImmunologyPathologyImmunotherapy +14

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

Franck Pagès, Bernhard Mlecnik, Florence Marliot, +95

The Lancet

Prognostic BiomarkersOncologyInternational ValidationMedicineImmunology +10

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability

Bernhard Mlecnik, Gabriela Bindea, Helen K. Angell, +29

Immunity

Tumor BiologyMedicineImmunologyStronger PredictorPathology +7

Lung adenocarcinoma promotion by air pollutants

William Hill, Emilia L. Lim, Clare E. Weeden, +320

Nature

AsthmaLung DepositionEnvironmental Lung DiseasesLung InflammationRespiratory Toxicology +6

Pan-cancer immunogenomic analyses reveal genotype-immunophenotype relationships and predictors of response to checkpoint blockade

Pornpimol Charoentong, Francesca Finotello, Mihaela Angelova, +5

Machine LearningGenotype-immunophenotype RelationshipsImmunologyPathologyImmunotherapy +14

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis

Bernhard Mlecnik, Gabriela Bindea, Amos Kirilovsky, +15

Science Translational Medicine

Evolution of Metastases in Space and Time under Immune Selection

Mihaela Angelova, Bernhard Mlecnik, Angela Vasaturo, +16

Cell

Systems BiologyImmune SelectionImmunologyBiological MicroenvironmentsImmunoediting +7

Immune evasion before tumour invasion in early lung squamous carcinogenesis

Céline Mascaux, Mihaela Angelova, Angela Vasaturo, +12

Nature

Immune EvasionMedicineImmunologyImmunoeditingPathology +6

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Christopher Abbosh, Alexander M. Frankell, Thomas Harrison, +300

Nature

EngineeringOncologic ImagingCancer DetectionMedicinePathology +6

The Link between the Multiverse of Immune Microenvironments in Metastases and the Survival of Colorectal Cancer Patients

Marc Van den Eynde, Bernhard Mlecnik, Gabriela Bindea, +23

Cancer Cell

Immune EvasionCancer ImmunosurveillanceMedicineImmunologyBiological Microenvironments +6